DSIP 5mg

DSIP (Delta Sleep-Inducing Peptide) is a naturally occurring nonapeptide (Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu) originally isolated from rabbits during slow-wave sleep. As a synthetic analog provided as a lyophilised powder for research use only, DSIP is used in laboratory settings to explore sleep architecture, stress modulation, and neuroendocrine regulation

Research Focus and Areas of Interest

1. Sleep Architecture Modulation

DSIP has been studied for its potential to influence deep (delta) sleep, enhance sleep efficiency, and reduce sleep latency—making it a tool for investigating sleep regulation mechanisms

2. Stress and Hormonal Regulation

Research suggests DSIP may modulate the hypothalamic-pituitary-adrenal (HPA) axis, affecting corticotropin release and stress resilience through endocrine pathways

3. Analgesia & Neuroprotection

DSIP exhibits potential pain-modulating effects, possibly via opioid receptor systems, and shows neuroprotective characteristics—demonstrated in models of oxidative stress and recovery after stroke

Conclusion

DSIP is a versatile research peptide offering insights into sleep depth, stress axis modulation, pain perception, and neural recovery mechanisms. Supplied strictly for research use only, it is not for therapeutic, human, or veterinary application.

Technical Information:

• Synonyms: Emideltide; Deltaran; DSIP nonapeptide

• Modified Single-Letter Sequence: Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu

• IUPAC Condensed Amino Acid Sequence: N-Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu-C

• Molecular Weight: ~848.8 g/mol

• CAS Number: 62568-57-4

• PubChem CID: 68816

• Further Reference: PubChem Link

Stability, Source, and Handling

• Stability: Stable up to 36 months when stored at –20 °C or colder, protected from light and moisture.

• Source: Synthesized via solid-phase peptide synthesis; supplied with Certificate of Analysis (COA) confirming purity and identity.

• Reconstitution: Reconstitute with sterile water or PBS under aseptic conditions; store aliquots at –80 °C after reconstitution to preserve integrity.

• Usage: Product is prepared for LABORATORY RESEARCH ONLY.