Fragment 176-191 5mg

Fragment 176-191 – 5 mg

Fragment 176-191 is a synthetic peptide fragment derived from the C-terminal section of human growth hormone (hGH), comprising amino acids 176 through 191. Supplied as a lyophilised powder for research use only, this fragment is used in laboratory investigations into fat metabolism, hormone signaling, and metabolic regulation. Because it isolates a functional segment of hGH, it allows focused study of lipid-related mechanisms without the broader systemic effects of full-length growth hormone.

Research Focus and Areas of Interest

1. Fat Breakdown Mechanisms

Fragment 176-191 promotes lipolysis (break-down of fat) and appears able to suppress lipogenesis (fat accumulation), making it useful for studies investigating how body fat is mobilised under different metabolic conditions.

2. Metabolic Regulation Pathways

Researchers use this fragment to examine effects on insulin sensitivity, glucose metabolism, and related enzymes, as well as its influence on the balance between energy storage and energy use.

3. Hormonal Cascade Interaction

Since Fragment 176-191 is a part of the hGH molecule, it helps in probing how fragments of GH might influence downstream hormonal axes — including potential effects on IGF-1 or feedback inhibition — without invoking full GH stimulation.

4. Safety & Endocrine Impacts

Animal studies suggest there may be contexts in which Fragment 176-191 influences glycaemic parameters; so labs often examine safety markers alongside metabolic outcomes when using this fragment.

Conclusion

Fragment 176-191 (5 mg) offers a controlled, high-dose research peptide fragment for probing fat metabolism, hormonal signaling, and metabolic regulation in lab settings. Supplied strictly for research use only, it is not intended for therapeutic, diagnostic, or veterinary use.

 

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Technical Information:

• Synonyms: HGH Fragment 176-191; hGH (176-191)

• Modified Single-Letter Sequence: Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe

• IUPAC Condensed Amino Acid Sequence: Tyrosine-Leucine-Arginine-Isoleucine-Valine-Glutamine-Cysteine-Arginine-Serine-Valine-Glutamate-Glycine-Serine-Cysteine-Glycine-Phenylalanine

• Molecular Weight:~1799.1 g/mol

• CAS Number: 66004-57-7

• PubChem CID: 16131230

• Further References: PubChem Entry

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Stability, Source, and Handling

• Stability: Stable for up to 36 months when stored at -20 °C or colder, protected from moisture and light.

• Source: Synthesised via solid-phase peptide synthesis; high purity with Certificate of Analysis (COA) confirmation.

• Reconstitution: Reconstitute in sterile water or PBS under aseptic conditions; aliquot and store at -80 °C after reconstitution to prevent degradation.

• Usage: Product is prepared for LABORATORY RESEARCH ONLY.