Triptorelin 100 mcg

Product Overview

Triptorelin is a synthetic decapeptide analogue of gonadotropin-releasing hormone (GnRH). It is widely used in laboratory research to investigate hypothalamic–pituitary–gonadal (HPG) axis signalling, receptor regulation, and endocrine feedback mechanisms.

The 100 mcg format is suitable for precision-based experimental work where controlled peptide quantities are required.

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Understanding Triptorelin

Triptorelin is structurally modified from endogenous GnRH through the substitution of D-tryptophan at position 6, a modification that increases receptor affinity and resistance to enzymatic degradation in experimental settings.

In research contexts, Triptorelin is studied for its effects on GnRH receptor activation, downstream luteinising hormone (LH) and follicle-stimulating hormone (FSH) release patterns, and endocrine system regulation.

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Mechanism of Action (Research Context)

Within laboratory models, Triptorelin is used to examine:

• GnRH receptor binding and activation

• Pituitary gonadotropin signalling pathways

• Pulsatile versus sustained GnRH analogue exposure

• Endocrine feedback loops within the HPG axis

Sustained exposure models are often explored to study receptor desensitisation and hormonal suppression mechanisms.

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Areas of Research Interest

Triptorelin is commonly investigated in experimental research related to:

• Neuroendocrine signalling

• Reproductive hormone regulation

• Pituitary receptor dynamics

• Hormonal feedback and suppression models

• Comparative GnRH analogue pharmacology

All applications are strictly non-clinical and laboratory-based.

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Conclusion

Triptorelin is a well-characterised GnRH analogue that serves as a valuable research tool for studying endocrine signalling and hormonal regulation. Its defined structure and receptor activity make it particularly useful in controlled laboratory investigations of the HPG axis. The 100 mcg presentation supports high-precision experimental design.

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Technical Details

• Synonyms: Arvekap, (D-Trp6)-GnRH, Triptoreline

• Sequence: XHWSYWLRPG

• IUPAC Condensed: H-Pyr-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH₂

• Molecular Weight: 1311.4 g/mol

• CAS Number: 57773-63-4

• PubChem CID: 25074470

• Reference: PubChem Link

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Storage & Stability

• Stability: Store lyophilised peptide at −20 °C

• Aliquot after reconstitution to avoid repeated freeze–thaw cycles

• Reconstituted peptide may be stored at 4 °C for a limited period

• Lyophilised peptide remains stable until expiry when stored at −20 °C

• Source: Biosynthesis

• Reconstitution: Reconstitute with bacteriostatic water

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Usage Disclaimer

This product is supplied for laboratory research purposes only.
Triptorelin sold by Pure Peptides UK is intended exclusively for scientific research and educational use. Purchase and use are restricted to licensed researchers.