Hexarelin (HEXA) – 2 mg
Hexarelin (HEXA) is a synthetic growth hormone secretagogue (GHS) belonging to the same peptide family as GHRP-2 and GHRP-6. Also known as Examorelin, it is a hexapeptide analog designed to selectively stimulate the release of growth hormone (GH) via interaction with the ghrelin receptor (GHS-R1a) in the pituitary and hypothalamus. Due to its stability and receptor affinity, Hexarelin is widely used in laboratory research examining endocrine regulation, tissue regeneration, and metabolic balance. Supplied as a lyophilised peptide, this product is prepared strictly for laboratory research only.
Research Focus and Areas of Interest
1. GH Secretion
Hexarelin is a potent stimulator of growth hormone release and has been used extensively to investigate the mechanisms of GH regulation. Its activity at both the pituitary and hypothalamic levels makes it valuable for exploring feedback loops in endocrine control and for comparing different classes of GH secretagogues.
2. Ghrelin Receptor Activity
As a synthetic ghrelin receptor agonist, Hexarelin serves as a research tool for studying the physiological roles of ghrelin, including energy metabolism, appetite signalling, and lipid regulation. It has been used to clarify how GHS peptides mimic endogenous ghrelin effects in controlled experimental settings.
3. Muscle and Tissue Regeneration
Laboratory studies suggest that Hexarelin may influence muscle growth, recovery, and tissue repair mechanisms through GH-mediated and independent pathways. Researchers continue to explore its effects on myogenesis, inflammation, and recovery from oxidative stress in tissue models.
4. Cardiovascular and Cellular Protection
Hexarelin has been examined for its potential to modulate cardiovascular performance and cellular resilience in experimental models. It may influence cardiomyocyte metabolism and promote protective signalling pathways, making it of interest in studies of cellular protection and longevity.
5. Comparative Peptide Research
As part of the GHRP family, Hexarelin is frequently compared with GHRP-2, GHRP-6, and Ipamorelin to study differences in receptor binding affinity, pharmacodynamics, and growth hormone release kinetics — enabling a more detailed understanding of structure–function relationships among GH secretagogues.
Conclusion
Hexarelin (HEXA) is a well-characterised research peptide that continues to play a central role in studies of growth hormone release, metabolic regulation, and cellular protection. Its stability, potency, and reproducible receptor activity make it an essential component in GH-related research. This product is intended strictly for laboratory research only and is not approved for human or veterinary use.
Technical Information:
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Synonyms: Examorelin; Examorelin [INN]; EP-23905
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Modified Single-Letter Sequence: H–X–A–W–F–K
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IUPAC Condensed Sequence: H–His–D–Trp(2-Me)–Ala–Trp–D–Phe–Lys–NH₂
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Molecular Weight: 887.0 g/mol
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CAS Number: 140703-51-1
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PubChem CID: 6918297
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Further Reference: PubChem Link
Stability, Source, and Handling
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Stability: Store lyophilised peptide at –20 °C. Avoid repeated freeze–thaw cycles. Once reconstituted, store at 4 °C for short-term use. Product remains stable until expiry when stored as directed.
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Source: Biosynthetic preparation with strict purity control.
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Reconstitution: Reconstitute with bacteriostatic water under aseptic laboratory conditions.
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Usage: Product is prepared for LABORATORY RESEARCH ONLY. Hexarelin supplied by Pure Peptides UK is intended solely for scientific and educational research use.
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