SEMAX 5mg

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Product Overview

SEMAX is a synthetic peptide widely referenced in scientific literature for its neuroprotective and neurogenic (neuro-restorative) properties. It is derived from a fragment of adrenocorticotropic hormone (ACTH 4–7) and was originally developed by the Institute of Molecular Genetics at the Russian Academy of Sciences.

Unlike the parent ACTH molecule, SEMAX is non-hormonal, making it particularly relevant for neurological and cognitive research without endocrine system activation. Its modified structure enhances peptide stability while retaining biological signalling relevance within the central nervous system.

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Research Background

SEMAX has been studied primarily in neuroscience and neurobiology research models. Scientific literature suggests that SEMAX may influence signalling pathways associated with neuronal survival, synaptic plasticity, and adaptive stress responses.

Research has also explored SEMAX’s interaction with neurotrophic factors such as brain-derived neurotrophic factor (BDNF), as well as its potential role in modulating inflammatory and oxidative stress responses within neural tissue.

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Areas of Research Interest

Current laboratory research involving SEMAX includes investigation into:

• Neuroprotection and neuronal survival mechanisms

• Neuroplasticity and synaptic signalling

• Cognitive and memory-related research models

• Stress-response and adaptive neural pathways

• Neurorestorative and recovery-focused studies

These research areas remain experimental and are explored strictly within controlled laboratory environments.

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Conclusion

SEMAX represents a well-documented peptide within neurological research, offering a non-hormonal platform for investigating neuroprotective and neuroplastic mechanisms. Its origin from ACTH fragments, combined with enhanced stability and CNS relevance, continues to make SEMAX a subject of interest in academic and laboratory-based research.

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Technical Details

• Synonyms: Semax, ACTH (4–7), Pro-Gly-Pro-, MEHFPGP, I5FAL2585H
• Sequence: MEHFPGP
• IUPAC Condensed: H-Met-Glu-His-Phe-Pro-Gly-Pro-OH
• Molecular Weight: 813.9 g/mol
• CAS Number: 80714-61-0
• PubChem CID: 9811102
• PubChem Link

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Storage & Stability

Stability:
Store lyophilised peptide at -20 °C. After reconstitution, aliquot to prevent repeated freeze–thaw cycles. Reconstituted peptide may be stored at 4 °C for a limited period. Lyophilised material remains stable until expiry when stored at -20 °C.

Source:
Biosynthesis

Reconstitution:
Reconstitute with bacteriostatic water.

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Usage Disclaimer

This product is supplied for laboratory research purposes only. SEMAX sold by Pure Peptides UK is intended solely for scientific research and educational use. Purchase and use are restricted to licensed researchers.